Marfan's disease progressive spastic paraplegia

例句：

1. 1. The patient was diagnosed with Marfan's disease and required regular follow-up care.
   这名患者被诊断出患有马凡氏综合征，需要定期跟进治疗。
2. 2. The patient's condition worsened over time, leading to progressive spastic paraplegia.
   患者的病情随着时间的推移而恶化，导致进展性痉挛性截瘫。
3. 3. The diagnosis of Marfan's disease has led to a better understanding of the genetic factors involved in this rare disorder.
   马凡氏综合征的诊断有助于更好地了解这种罕见病症所涉及的遗传因素。