actinic keratosis

例句：

1. 1. The patient's skin was severely affected by the disease.
   患者的皮肤严重受到了这种疾病的影响。
2. 2. This condition is often seen in people with long-term exposure to sunlight.
   这种状况通常在长期暴露于阳光的人中出现。
3. 3. The treatment for this disease involves a combination of topical and systemic medications.
   治疗这种病需要局部和系统性药物的结合使用。