be of no effect

例句：

1. 1. The new policywas supposed to make a big difference, but it turned out to be of no effect.
   新政策本应产生重大影响，但事实证明它毫无作用。
2. 2.The medicine is of no effect on my headache.
   这种药对我头痛没有任何效果。
3. 3. Despite the efforts, the plan was of no effect on the company's profits.
   尽管做出了努力，这个计划对公司的利润没有任何影响。