derangement

例句：

1. 1. Hewas so disoriented that he couldn't find his way home.
   他迷失了方向，找不到回家的路。
2. 2. The patient's derangement made it difficult for the doctor to diagnose the illness.
   患者的精神状态使医生难以诊断出疾病。
3. 3.The sudden loss of her parents left her in a state of derangement.
   她突然失去了父母，陷入了精神错乱的状态。