gunned refractory

例句：

1. 1. The patient was diagnosed with an intractable disease.
   这位病人被诊断出患有一种难以治愈的疾病。
2. 2. The old man refused to give up his cherished hobby despite the intractable nature of the disease.
   尽管疾病难以治愈，但那位老人还是坚持他心爱的爱好。
3. 3. The scientist's research on this refractory virus has been a significant breakthrough in medical science.
   科学家对这种顽固病毒的研究在医学科学上取得了重大突破。