increase of circulating anticoagulant

例句：

1. 1. The doctor prescribed an increased dose of medication for her condition.
   医生为她的状况开了增加剂量的药物。
2. 2.The study found a significant increase in the number of heart attacks during the holiday season.
   研究发现，节假日期间心脏病发作的数量显著增加。
3. 3.The company announced a 5% increase in its quarterly profit forecast.
   该公司宣布季度利润预测上调了5%。