malignant change

例句：

1. 1. The patient's condition has worsened significantly since the surgery.
   手术后，患者的病情明显恶化。
2. 2. The cancer cells are rapidly proliferating and causing malignant changes in the body.
   癌细胞迅速增殖，导致身体发生恶性变化。
3. 3. Researchers have discovered a new drug that can effectively treat malignant changes in the brain.
   研究人员发现了一种新药，可以有效治疗大脑的恶性变化。