pathological change

例句：

1. 1.The patient's condition worsened after the surgery.
   手术后，患者的病情恶化了。
2. 2. The doctor diagnosed the patient with a pathological change in his heart.
   医生诊断出患者心脏有病理变化。
3. 3. The study found that certain genetic mutations can lead to pathological changes in the body.
   研究发现某些基因突变会导致身体出现病理变化。