what's up

例句：

1. 1. What's up with you?
   你怎么了？
2. 2. I just saw your friend and asked if everything was okay.
   我刚看到你的朋友，问他一切还好吗。
3. 3.He looked a bit down and asked me how I was doing.
   他看起来有点沮丧，问我过得怎么样。